منابع مشابه
Normal Aging of the brain
With the increase of the mean age of our populations, neurodegenerative diseases are becoming more and more important. This is also true for the early diagnosis of neurodegeneration and to allow for an early therapeutic intervention since degenerative diseases begin long before the patient experiences any symptoms. It can be months or years before clinical symptoms become obvious. Imaging with ...
متن کاملTask-related brain oscillations in normal aging
During the past few years, many researchers have demonstrated the importance of the agerelated changes in spontaneous electroencephalography. However, very little research on of the event-related responses of oscillations connections has been used to examine the changes during normal aging. The aim of the present study was to investigate age-related changes of task-related brain oscillations, w...
متن کاملBrain cholesterol in normal and pathological aging.
Correct lipid homeostasis at the plasma membrane is essential for cell survival and performance. These are critically challenged in the aging brain. Changes in the levels of cholesterol, a major membrane component especially enriched in neurons, accompany the brain aging process. They also occur in neurodegenerative diseases. Understanding the causes and consequences of these changes is a cruci...
متن کاملAltered synaptic dynamics during normal brain aging.
What is the neuroanatomical basis for the decline in brain function that occurs during normal aging? Previous postmortem studies have blamed it on a reduction in spine density, though results remain controversial and spine dynamics were not assessed. We used chronic in vivo two-photon imaging of dendritic spines and axonal boutons in somatosensory cortex for up to 1 year in thy1 GFP mice to tes...
متن کاملFactors influencing decisions on organ donation in brain death patients
Organ donation is an integral part of the health care system. Many patients who have had an accident or have undergone a progressive disease are in need of an organ transplant and if they do not receive the required organ they would die. It is important to know that the most important source of organ donation is the brain death patients. It is highly essential to determine the pivotal factors t...
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ژورنال
عنوان ژورنال: The Gerontologist
سال: 2001
ISSN: 1758-5341,0016-9013
DOI: 10.1093/geront/41.6.716